CD16 anticorps (Biotin)
Aperçu rapide pour CD16 anticorps (Biotin) (ABIN7472969)
Antigène
Voir toutes CD16 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- Recognizes human CD16, a 50-65kD cell surface molecule, which is the low affinity receptor for IgG (FcR III). CD16 exists as a transmembranous form (Fc gammaRIIIA, or CD16A) and a glycosyl phosphatidylinositol (GPI) anchored form (Fc gammaRIIIB, or CD16B). CD16A is expressed by NK cells, some T cells, and macrophages, whereas CD16B is primarily expressed by granulocytes. In addition, CD16B exists as two allelic variants NA1 and NA2. Recognizes all polymorphonuclear cells irrespective on their NA phenotype. Studies show that the Recognizes an epitope in the first membrane-distal domain of Recognizes both CD16A and CD16B.
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Purification
- Protein G purified
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Immunogène
- CD34 antigen.
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Isotype
- IgG1
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Indications d'application
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Approved: Flo (1:1 - 1:10)
Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL. Method sheets are available on request. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. -
Commentaires
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- PBS, pH 7.4, 0.09 % sodium azide, 1 % BSA.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- avoid freeze thaw cycles. Store undiluted.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles. Store undiluted.
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- CD16
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Autre désignation
- CD16
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Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
Antigène
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